Dasharo e Qubes-OS
Dasharo is an open-source firmware distribution focusing on seamless deployment, clean and simple code, long-term maintenance, professional support, transparent validation, superior documentation, privacy-respecting implementation, liberty for the owners and trustworthiness for all.
Qubes OS is a free and open-source, security-oriented operating system for single-user desktop computing. Qubes OS leverages Xen-based virtualization to allow for the creation and management of isolated compartments called qubes.